Recovery is a round-the-clock process, and patients can’t always see you when triggers and cravings arise. RESET® and RESET-O® give you 24/7 support on your patients' smartphone.1,2*

 

Put the power of a 24/7 tool in patients’ hands

Provide anytime, anywhere access to evidence-based approaches, like cognitive behavioral therapy, fluency training, and contingency management, with the clinically proven prescription digital therapeutic that meets their needs.4,5

 
 
 

RESET

RESET supports outpatient treatment

RESET, for substance use disorder (SUD), is a 12-week, FDA-authorized prescription digital therapeutic (PDT) clinically proven to help people in outpatient treatment abstain from substance use and stay in treatment longer.1,3

 

RESET

RESET supports outpatient treatment

RESET, for substance use disorder (SUD), is a 12-week, FDA-authorized prescription digital therapeutic (PDT) clinically proven to help people in outpatient treatment abstain from substance use and stay in treatment longer.1,3

RESET

A 12-week clinical study showed that patients using reSET were more than 2x more likely to abstain from substance use than those who didn’t use RESET.5*

*During the last 4 weeks of trial.

For individuals with substance use disorder, RESET® is the first FDA-authorized prescription digital therapeutic that’s proven to increase abstinence and treatment retention.5,6 Patients prescribed reSET download it to their phone for secure, discreet, convenient access to therapy, interactive learning, and support. reSET lets them practice what you’ve taught them anytime, anywhere, and report daily triggers, cravings, and substance use - so they feel more engaged and supported between appointments, and you get a clearer picture of where they are in their recovery journey.5

  • RESET can help patients stay on their recovery journey*

    *During 12 weeks of treatment.

  • Track patient cravings and triggers

    Patients can record substance use, cravings, and triggers to make in-person or remote therapy more productive and meaningful.5

  • Get therapy on demand

    Interactive cognitive behavioral therapy lessons help patients learn new skills they can use in everyday situations to support their recovery journey.5

  • Improve coping strategies

    Questions at the end of each lesson help patients remember important ideas and practice skills to stay in treatment.5

  • Provide encouragement with rewards

    Make use of reSET’s available contingency management capabilities to provide patients with tangible rewards, like accomplishment badges and gift cards, to reinforce positive, healthier behaviors.5

    Rewards may be virtual (nonmonetary) or in the form of gift cards (possibly ranging in amounts different from those shown here) and may be at the discretion of the prescriber.

IN A 12-WEEK CLINICAL STUDY OF PEOPLE WITH SUD

Patients who used RESET in outpatient treatment were 2 times more likely to abstain from substance use than those who didn’t use RESET.1

Treatment with RESET did not demonstrate a significant difference in unanticipated adverse events compared with treatment as usual.3

 

RESET-O

RESET-O supports outpatient treatment

RESET-O, for opioid use disorder (OUD), is a 12-week, FDA-authorized PDT clinically proven to help people in outpatient treatment and on transmucosal buprenorphine stay in their treatment longer.2

 

RESET-O

RESET-O supports outpatient treatment

RESET-O, for opioid use disorder (OUD), is a 12-week, FDA-authorized PDT clinically proven to help people in outpatient treatment and on transmucosal buprenorphine stay in their treatment longer.2

RESET-O

*During 12 weeks of treatment. Those who didn’t add reSET-O received treatment as usual.

For individuals with opioid use disorder, RESET-O® is the only FDA-authorized prescription digital therapeutic that’s proven to help patients stay in treatment longer.4,7 It works in a way that meets patients where they already are, on their smartphones, so they can turn screen time into therapy time. Patients prescribed RESET-O download it to their phone for secure, discreet, and convenient access to therapy, interactive learning, and support.

  • Meet the opioid crisis head on with RESET-O

  • Track patient cravings and triggers

    Patients can record substance use, cravings, and triggers to make in-person or remote therapy more productive and meaningful.4

  • Get buprenorphine reminders

    Patients can set up daily reminders to take their medication.4

  • Get therapy on demand

    Interactive cognitive behavioral therapy lessons help patients learn new skills they can use in everyday situations to support their recovery journey.4

  • Improve coping strategies

    Questions at the end of each lesson help patients remember important ideas and practice skills to stay in treatment.4

  • Provide encouragement with rewards

    Make use of RESET-O’s available contingency management capabilities to provide patients with tangible rewards, like accomplishment badges and gift cards, to reinforce positive, healthier behaviors.4

    Rewards may be virtual (nonmonetary) or in the form of gift cards (possibly ranging in amounts different from those shown here) and may be at the discretion of the prescriber.

IN A 12-WEEK CLINICAL STUDY OF PEOPLE WITH OUD WHO STAYED IN TREATMENT2

82%

Of people who added RESET-O to their buprenorphine stayed in treatment

vs.

68%

Who didn’t add RESET-O to their buprenorphine stayed in treatment

The observed adverse events were of a type and frequency to be anticipated in a large population of patients with OUD or associated with buprenorphine pharmacotherapy, particularly during the induction phase.2

The adverse events observed were not determined to be device related.2

Clinician Dashboard

Optimize treatment and enrich sessions using real-world patient data4,5

  • Clinician Dashboard

    Using objective, measurable data, the Clinician Dashboard helps you gain deeper, big picture insight that can add up to a more complete view of patients and their treatment trajectory.

  • Core lessons

    RESET and RESET-O give patients access to 12 weeks of core lessons in cognitive behavioral therapy.4,5 RESET-O includes lessons specific to opioid use disorder. Both prescription digital therapeutics allow you to follow patient progress throughout treatment.

    -Review which lessons your patient has completed and when4,5
    -Reassign lessons as needed for more individualized treatment4,5

  • Rewards

    Provide encouragement with rewards that can help patients stay motivated on their recovery journey.4,5

    -Set up rewards for patients who successfully complete a lesson or a negative drug screen4,5
    -Select the type of rewards you want them to receive, such as badges or gift cards4,5
    -Turn off monetary rewards if you do not want to include them in your practice4,5

  • Calendar

    The calendar feature lets you access key information quickly and easily, so you can guide patient conversations and keep your practice running smoothly.

    -Store and organize appointment attendance and drug screen data4,5
    -Quickly access compliance information before patient meetings4,5
    -Find information easily thanks to the simple color-coded system4,5

  • Cravings and triggers

    As patients progress through the 12-week program, they’re encouraged to enter real-time data on cravings and triggers so you can track their progress with at-a-glance charting.

    Review patient-reported data on substance use, cravings, and triggers4,5
    -View ready-made data visualizations, such as charts and graphs4,5
    -Identify patterns and better understand patient challenges to recovery4,5

RESET® Indications for Use:

RESET is intended to provide cognitive behavioral therapy, as an adjunct to a contingency management system, for patients 18 years of age and older, who are currently enrolled in outpatient treatment under the supervision of a clinician. reSET is indicated as a 12-week (90 day) prescription-only treatment for patients with substance use disorder (SUD), who are not currently on opioid replacement therapy, who do not abuse alcohol solely, or who do not abuse opioids as their primary substance of abuse.

It is intended to:

  • increase abstinence from a patient’s substances of abuse during treatment, and
  • increase retention in the outpatient treatment program.

RESET® Important Safety Information for Patients:

Warnings/precautions: Do not use RESET to communicate any emergency, urgent or critical information. RESET does not include features that can send alerts or warnings to your clinician. If you have feelings or thoughts of harming yourself or others, please dial 911 or go to the nearest emergency room.

RESET is intended for patients whose primary language is English with a reading level of 7th grade or above, who have access to an Android/iOS tablet or smartphone, and who are familiar with the use of smartphone applications (apps). You should be able to upload data periodically, i.e. have internet/wireless connection access.

RESET is not intended to be used as stand-alone therapy for substance use disorder (SUD) and does not replace care by your provider or outpatient treatment. RESET is not a substitute for your medications. You should continue to take your medications as directed by your provider.

The long-term benefit of treatment with RESET on abstinence has not been evaluated in studies lasting beyond 12 weeks (90 days) in the SUD population. The ability of RESET to prevent potential relapse after treatment discontinuation has not been studied.

The safety and effectiveness of RESET has not been established in patients enrolled in opioid treatment programs reporting opioids as their primary substance of abuse.

RESET-O® Indications for Use:

RESET-O prescription digital therapeutic is a 12-week (84 day) software application intended to increase retention of patients with opioid use disorder (OUD) in outpatient treatment by providing cognitive behavioral therapy, as an adjunct to outpatient treatment that includes transmucosal buprenorphine and contingency management, for patients 18 years or older who are currently under the supervision of a clinician. reSET-O is indicated as a prescription-only digital therapeutic.

RESET-O® Important Safety Information for Patients:

Warnings/precautions: Do not use RESET-O to communicate any emergency, urgent or critical information. RESET-O does not include features that can send alerts or warnings to your clinician. If you have feelings or thoughts of harming yourself or others, please dial 911 or go to the nearest emergency room.

RESET-O is intended for patients whose primary language is English with a reading level of 7th grade or above, who have access to an Android/iOS tablet or smartphone, and who are familiar with the use of smartphone applications (apps). You should be able to upload data periodically, i.e. have internet/wireless connection access.

RESET-O is not intended to be used as stand-alone therapy for Opioid Use Disorder (OUD) and does not replace care by your provider or outpatient treatment. RESET-O is not a substitute for your medications. You should continue to take your medications as directed by your provider.

The long-term benefit of RESET-O has not been evaluated in studies lasting beyond 12 weeks (84 days) in the OUD population. The ability of reSET-O to prevent potential relapse after therapy discontinuation has not been studied.

 

References:

1. Substance Abuse and Mental Health Services Administration. Key Substance Use and Mental Health Indicators in the United States: Results From the 2020 National Survey on Drug Use and Health. US Department of Health and Human Services; 2021. HHS publication no. PEP21-07-01-003, NSDUH Series H-56. Accessed April 15, 2022.
https://www.samhsa.gov/data/sites/default/files/reports/rpt35325/NSDUHFFRPDFWHTMLFiles2020/2020NSDUHFFR1PDFW102121.pdf

2. Medication-assisted treatment (MAT). Substance Abuse and Mental Health Services Administration. Updated March 30, 2022. Accessed April 15, 2022.
https://www.samhsa.gov/medication-assisted-treatment

3. Data on file. Pear Therapeutics. 2021

4. RESET-O Clinician directions for use. Pear Therapeutics, Inc. 2020.

5. RESET Clinician directions for use. Pear Therapeutics, Inc. 2020.

6. FDA permits marketing of mobile medical application for substance use disorder. News Release. Silver Spring, MD: US Food and Drug Administration. September 14, 2017. Accessed May 18, 2020. https://www.fda.gov/news-events/press-announcements/fda-permits-marketing-mobile-medical-application-substance-use-disorder

7. FDA clears mobile medical app to help those with opioid use disorder stay in recovery programs. News release. Silver Spring, MD: US Food and Drug Administration. December 10, 2018. Accessed May 18, 2020. https://www.fda.gov/news-events/press-announcements/fda-clears-mobile-medical-app-help-those-opioid-use-disorder-stay-recovery-programs